PReS-FINAL-2132: Defining criteria for high disease activity in juvenile idiopathic arthritis: definition and validation of juvenile arthritis disease activity score cutoffs

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PReS-FINAL-2132: Defining criteria for high disease activity in juvenile idiopathic arthritis: definition and validation of juvenile arthritis disease activity score cutoffs

Introduction Assessment of disease activity is a fundamental component of the clinical evaluation of children with juvenile idiopathic arthritis (JIA) because persistently active disease plays a major role in causing joint damage and physical functional disability. Furthermore, measurement of the level of disease activity over time is important in monitoring the disease course and in assessing ...

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Final validation of a new composite disease activity score for juvenile idiopathic arthritis: the Juvenile Arthritis Disease Activity Score (JADAS)

Materials and methods The JADAS is composed of the following measures: 1) physician's global assessment (0–10); 2) parent's global assessment (0–10); 3) active joint count (assessed in 71, 27 or 10 joints); 4) ESR (normalized to 0–10). It yields a score ranging from 0 to 40, 57 or 101, depending on whether the whole 71-joint count (JADAS-71) or the 27joint (JADAS-27) or 10-joint (JADAS-10) redu...

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Definition of improvement in juvenile idiopathic arthritis using the juvenile arthritis disease activity score.

OBJECTIVE The aim of this study was to define improvement thresholds for the Juvenile Arthritis Disease Activity Score (JADAS). METHODS Physicians' and parents' judgements on treatment efficacy, the ACR paediatric response measure (PedACR) and JADAS were extracted from BIKER. Patients were categorized by baseline classes in the 10-joint JADAS (JADAS10) as low (5 to <15), moderate (15 to <25) ...

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PReS-FINAL-2163: Disease activity in a juvenile idiopathic arthritis population after 5 years follow-up

Methods A cross sectional study at the 5 year of follow-up from a JIA patients cohort, diagnosed between 2000-2008 was carried out. Treatment strategy followed the Portuguese recommendations for the treatment of JIA. The data were collected using Reuma.pt (Portuguese Register of Rheumatic Diseases). At the 5 year JADAS-27 was evaluated and used to identify patients who met the preliminary crite...

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Juvenile arthritis disease activity score is a better reflector of active disease than the disease activity score 28 in adults with polyarticular juvenile idiopathic arthritis

A considerable proportion of children with polyarticular juven-ile idiopathic arthritis (polyJIA) experience active disease into adulthood. However, there is no validated disease activity measure for adults with polyJIA, and they are often assessed using the disease activity score 28 (DAS28). DAS28 is validated in adults with rheumatoid arthritis (RA), and determines qualification for biologica...

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ژورنال

عنوان ژورنال: Pediatric Rheumatology

سال: 2013

ISSN: 1546-0096

DOI: 10.1186/1546-0096-11-s2-p145